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容易患感冒都是基因惹的祸

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Tried everything and still got the flu this year? While some friends and colleagues always seem to avoid it. Well, they may have more than luck on their side. Scientists have discovered that however hard you try to avoid it; flu is in your genes

A study on British volunteers shows that some people are genetically predisposed to stave off the illness, while others are struck down year after year

Researchers inoculated 17 healthy people with the flu virus and monitored their progress for five days

Of the sample, nine became ill and the rest showed no symptoms at all

总感冒?基因惹的祸!

Using technology usually employed in satellite imaging, they examined the genes in the subjectsblood samples every eight hours

Those who became sick developed an acute inflammation on certain genes 36 hours before the symptoms set in. This "genetic signature" was most marked in those who were suffering the worst

Meanwhile, those who remained fine were found to have activated a totally different genetic signature

The scientists interpreted this signature as an "anti-stress response" that showed their bodies were actively fighting off the virus. This discovery raises the possibility that experts could find a way to detect flu early, and take preventative action before the worst effects develop

Professor Peter Openshaw, of the Centre for Respiratory Infection at Imperial College, said: "This is a very important science. It has very big implications for many infectious diseases, not only flu

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