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Epigenetics and health 表观遗传学与健康 Grandma s curse 祖母的诅咒 Some of the effects of smoking may be passed fromgrandmother to grandchild 祖母吸烟产生的影响可以会遗传至孙子或孙女 Think of your grandchildren! 想想你的孙辈吧! ONE of biology s hottest topics is epigenetics. 当今生物学最热的话题之一是表观遗传学， The term itself covers a multitude of sins. 这个术语本身就涵盖了许多宗罪。 Strictly speaking, it refers to the regulation of gene expression by the chemicalmodification of DNA, or of the histone proteins in which DNA is usually wrapped. 严格来说，表观遗传学研究的是DNA或含有DNA的组蛋白化学改性中的基因表达调控现象。 This modification is either the addition of methyl groups to the DNA or of acetyl groups tothe histones. 这种改性或者是甲基增至DNA中，或者是乙酰基增加到组蛋白中。 Methylation switches genes off. 甲基化作用关闭基因， Acetylation switches them on. 乙酰化作用启动基因。 | 
