多运动可减少患老年痴呆症风险
<p><span word="A">A</span> <span word="new">new</span> <span word="study">study</span> <span word="finds">finds</span> <span word="that">that</span> <span word="an">an</span> <span word="active">active</span> <span word="lifestyle">lifestyle</span> <span word="may">may</span> <span word="help">help</span> <span word="protect">protect</span> <span word="against">against</span> <span word="Alzheimer">Alzheimer</span>'<span word="s">s</span>-<span word="related">related</span> <span word="brain">brain</span> <span word="changes">changes</span> <span word="in">in</span> <span word="people">people</span> <span word="who">who</span> <span word="have">have</span> <span word="a">a</span> <span word="well">well</span>-<span word="known">known</span> <span word="genetic">genetic</span> <span word="risk">risk</span> <span word="factor">factor</span>. <span word="This">This</span> <span word="factor">factor</span> <span word="is">is</span> <span word="the">the</span> <span word="e">e</span>4 <span word="allele">allele</span> (<span word="version">version</span>) <span word="of">of</span> <span word="the">the</span> <span word="apolipoprotein">apolipoprotein</span> <span word="E">E</span> (<span word="APOE">APOE</span>) <span word="gene">gene</span>.</p><p>一项新的研究表明经常运动能帮助那些有老年痴呆症遗传因素的人们降低患病风险。这种遗传因素是载脂蛋白<span word="Ee">Ee</span>4等位基因。</p><p>"<span word="The">The</span> <span word="presence">presence</span> <span word="of">of</span> <span word="an">an</span> <span word="APOE">APOE</span> <span word="e">e</span>4 <span word="allele">allele</span> <span word="is">is</span> <span word="the">the</span> <span word="most">most</span> <span word="established">established</span> <span word="genetic">genetic</span> <span word="risk">risk</span> <span word="factor">factor</span> <span word="for">for</span> <span word="Alzheimer">Alzheimer</span> <span word="disease">disease</span>, <span word="with">with</span> <span word="a">a</span> <span word="higher">higher</span> <span word="percentage">percentage</span> <span word="of">of</span> <span word="individuals">individuals</span> <span word="with">with</span> <span word="Alzheimer">Alzheimer</span>'<span word="s">s</span> <span word="disease">disease</span> <span word="having">having</span> <span word="an">an</span> <span word="e">e</span>4 <span word="allele">allele</span> <span word="in">in</span> <span word="comparison">comparison</span> <span word="with">with</span> <span word="the">the</span> <span word="general">general</span> <span word="population">population</span>," <span word="the">the</span> <span word="authors">authors</span> <span word="write">write</span> <span word="in">in</span> <span word="the">the</span> <span word="article">article</span> <span word="published">published</span> <span word="online">online</span> <span word="Jan">Jan</span>. 9 <span word="in">in</span> <span word="the">the</span> <span word="journal">journal</span> <span word="Archives">Archives</span> <span word="of">of</span> <span word="Neurology">Neurology</span>. <span word="It">It</span>'<span word="s">s</span> <span word="been">been</span> <span word="suggested">suggested</span> <span word="that">that</span> <span word="the">the</span> <span word="presence">presence</span> <span word="or">or</span> <span word="absence">absence</span> <span word="of">of</span> <span word="this">this</span> <span word="gene">gene</span> <span word="variant">variant</span> <span word="might">might</span> <span word="affect">affect</span> <span word="the">the</span> <span word="relationship">relationship</span> "<span word="between">between</span> <span word="lifestyle">lifestyle</span> <span word="factors">factors</span> <span word="such">such</span> <span word="as">as</span> <span word="exercise">exercise</span> <span word="engagement">engagement</span> <span word="and">and</span> <span word="risk">risk</span> <span word="of">of</span> <span word="cognitive">cognitive</span> <span word="decline">decline</span> <span word="and">and</span> <span word="dementia">dementia</span>," <span word="added">added</span> <span word="researcher">researcher</span> <span word="Denise">Denise</span> <span word="Head">Head</span> <span word="and">and</span> <span word="colleagues">colleagues</span> <span word="at">at</span> <span word="Washington">Washington</span> <span word="University">University</span>, <span word="St">St</span>. <span word="Louis">Louis</span>.</p><p>“载脂蛋白<span word="e">e</span>4等位基因的存在是患老年痴呆症的最大潜在威胁，患有老年痴呆症的人群跟普通人群相比，他们体内含有的<span word="e">e</span>4等位基因比例更高。”该研究的作者在《神经学档案》1月9日的电子刊上如此说道，“据研究这种基因的存在与否可能会影响运动量等生活方式和认知功能下降及痴呆之间的关系。”研究员<span word="Denise">Denise</span> <span word="Head">Head</span>及其圣路易华盛顿大学的同事们补充说。</p>
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