国际英语资讯:WHO discontinues hydroxychloroquine, lopinavir/ritonavir trial for COVID-19 treatment
<p><span word="GENEVA">GENEVA</span>, <span word="July">July</span> 4-- <span word="The">The</span> <span word="World">World</span> <span word="Health">Health</span> <span word="Organization">Organization</span> (<span word="WHO">WHO</span>) <span word="announced">announced</span> <span word="on">on</span> <span word="Saturday">Saturday</span> <span word="that">that</span> <span word="it">it</span> <span word="was">was</span> <span word="discontinuing">discontinuing</span> <span word="hydroxychloroquine">hydroxychloroquine</span> <span word="and">and</span> <span word="lopinavir">lopinavir</span>/<span word="ritonavir">ritonavir</span> <span word="arms">arms</span> <span word="for">for</span> <span word="its">its</span> <span word="Solidarity">Solidarity</span> <span word="Trial">Trial</span>, <span word="citing">citing</span> <span word="little">little</span> <span word="or">or</span> <span word="no">no</span> <span word="reduction">reduction</span> <span word="in">in</span> <span word="the">the</span> <span word="mortality">mortality</span> <span word="of">of</span> <span word="hospitalized">hospitalized</span> <span word="COVID">COVID</span>-19 <span word="patients">patients</span>.</p><p><span word="The">The</span> <span word="WHO">WHO</span> <span word="said">said</span> <span word="the">the</span> <span word="decision">decision</span> <span word="was">was</span> <span word="in">in</span> <span word="light">light</span> <span word="of">of</span> <span word="the">the</span> <span word="evidence">evidence</span> <span word="from">from</span> <span word="the">the</span> <span word="Solidarity">Solidarity</span> <span word="Trial">Trial</span> <span word="interim">interim</span> <span word="results">results</span>.</p><p>"<span word="These">These</span> <span word="interim">interim</span> <span word="trial">trial</span> <span word="results">results</span> <span word="show">show</span> <span word="that">that</span> <span word="hydroxychloroquine">hydroxychloroquine</span> <span word="and">and</span> <span word="lopinavir">lopinavir</span>/<span word="ritonavir">ritonavir</span> <span word="produce">produce</span> <span word="little">little</span> <span word="or">or</span> <span word="no">no</span> <span word="reduction">reduction</span> <span word="in">in</span> <span word="the">the</span> <span word="mortality">mortality</span> <span word="of">of</span> <span word="hospitalized">hospitalized</span> <span word="COVID">COVID</span>-19 <span word="patients">patients</span> <span word="when">when</span> <span word="compared">compared</span> <span word="to">to</span> <span word="standard">standard</span> <span word="of">of</span> <span word="care">care</span>. <span word="Solidarity">Solidarity</span> <span word="trial">trial</span> <span word="investigators">investigators</span> <span word="will">will</span> <span word="interrupt">interrupt</span> <span word="the">the</span> <span word="trials">trials</span> <span word="with">with</span> <span word="immediate">immediate</span> <span word="effect">effect</span>," <span word="the">the</span> <span word="WHO">WHO</span> <span word="said">said</span> <span word="in">in</span> <span word="a">a</span> <span word="press">press</span> <span word="release">release</span>.</p><p><span word="But">But</span> <span word="the">the</span> <span word="organization">organization</span> <span word="said">said</span> <span word="this">this</span> <span word="decision">decision</span> <span word="applies">applies</span> <span word="only">only</span> <span word="to">to</span> <span word="hospitalized">hospitalized</span> <span word="patients">patients</span> <span word="and">and</span> <span word="does">does</span> <span word="not">not</span> <span word="affect">affect</span> <span word="the">the</span> <span word="possible">possible</span> <span word="evaluation">evaluation</span> <span word="in">in</span> <span word="other">other</span> <span word="studies">studies</span> <span word="of">of</span> <span word="hydroxychloroquine">hydroxychloroquine</span> <span word="or">or</span> <span word="lopinavir">lopinavir</span>/<span word="ritonavir">ritonavir</span> <span word="in">in</span> <span word="non">non</span>-<span word="hospitalized">hospitalized</span> <span word="patients">patients</span> <span word="or">or</span> <span word="as">as</span> <span word="pre">pre</span>- <span word="or">or</span> <span word="post">post</span>-<span word="exposure">exposure</span> <span word="prophylaxis">prophylaxis</span> <span word="for">for</span> <span word="COVID">COVID</span>-19.</p><p><span word="The">The</span> <span word="Solidarity">Solidarity</span> <span word="Trial">Trial</span> <span word="was">was</span> <span word="established">established</span> <span word="by">by</span> <span word="the">the</span> <span word="WHO">WHO</span> <span word="in">in</span> <span word="March">March</span> <span word="to">to</span> <span word="find">find</span> <span word="an">an</span> <span word="effective">effective</span> <span word="COVID">COVID</span>-19 <span word="treatment">treatment</span> <span word="for">for</span> <span word="hospitalized">hospitalized</span> <span word="patients">patients</span>. <span word="It">It</span> <span word="was">was</span> <span word="originally">originally</span> <span word="designed">designed</span> <span word="to">to</span> <span word="have">have</span> <span word="five">five</span> <span word="trial">trial</span> <span word="arms">arms</span>, <span word="including">including</span> <span word="standard">standard</span> <span word="or">or</span> <span word="usual">usual</span> <span word="care">care</span> <span word="provided">provided</span> <span word="to">to</span> <span word="COVID">COVID</span>-19 <span word="patients">patients</span>, <span word="remdesivir">remdesivir</span>, <span word="lopinavir">lopinavir</span>/<span word="ritonavir">ritonavir</span> <span word="combined">combined</span>, <span word="lopinavir">lopinavir</span>/<span word="ritonavir">ritonavir</span> <span word="combined">combined</span> <span word="with">with</span> <span word="interferon">interferon</span> <span word="beta">beta</span>, <span word="and">and</span> <span word="hydroxychloroquine">hydroxychloroquine</span> <span word="or">or</span> <span word="chloroquine">chloroquine</span>.</p><p><span word="By">By</span> <span word="enrolling">enrolling</span> <span word="patients">patients</span> <span word="in">in</span> <span word="multiple">multiple</span> <span word="countries">countries</span>, <span word="the">the</span> <span word="Solidarity">Solidarity</span> <span word="Trial">Trial</span> <span word="aims">aims</span> <span word="to">to</span> <span word="rapidly">rapidly</span> <span word="discover">discover</span> <span word="whether">whether</span> <span word="any">any</span> <span word="of">of</span> <span word="the">the</span> <span word="drugs">drugs</span> <span word="slow">slow</span> <span word="disease">disease</span> <span word="progression">progression</span> <span word="or">or</span> <span word="improve">improve</span> <span word="survival">survival</span>.</p>
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