国际英语资讯:Spotlight: Clinical trial shows remdesivir accelerates recovery from advanced COVID-19 patie
<p><span word="WASHINGTON">WASHINGTON</span>, <span word="April">April</span> 29-- <span word="Hospitalized">Hospitalized</span> <span word="patients">patients</span> <span word="with">with</span> <span word="advanced">advanced</span> <span word="COVID">COVID</span>-19 <span word="and">and</span> <span word="lung">lung</span> <span word="involvement">involvement</span> <span word="who">who</span> <span word="received">received</span> <span word="remdesivir">remdesivir</span> <span word="recovered">recovered</span> <span word="faster">faster</span> <span word="than">than</span> <span word="similar">similar</span> <span word="patients">patients</span> <span word="who">who</span> <span word="received">received</span> <span word="placebo">placebo</span>, <span word="according">according</span> <span word="to">to</span> <span word="a">a</span> <span word="release">release</span> <span word="from">from</span> <span word="the">the</span> <span word="U">U</span>.<span word="S">S</span>. <span word="National">National</span> <span word="Institute">Institute</span> <span word="of">of</span> <span word="Allergy">Allergy</span> <span word="and">and</span> <span word="Infectious">Infectious</span> <span word="Diseases">Diseases</span> (<span word="NIAID">NIAID</span>) <span word="on">on</span> <span word="Wednesday">Wednesday</span>.</p><p><span word="The">The</span> <span word="conclusion">conclusion</span> <span word="came">came</span> <span word="out">out</span> <span word="of">of</span> <span word="preliminary">preliminary</span> <span word="data">data</span> <span word="analysis">analysis</span> <span word="from">from</span> <span word="a">a</span> <span word="randomized">randomized</span>, <span word="controlled">controlled</span> <span word="trial">trial</span> <span word="involving">involving</span> 1,063 <span word="patients">patients</span>, <span word="which">which</span> <span word="began">began</span> <span word="on">on</span> <span word="Feb">Feb</span>. 21.</p><p><span word="Preliminary">Preliminary</span> <span word="results">results</span> <span word="indicated">indicated</span> <span word="that">that</span> <span word="patients">patients</span> <span word="who">who</span> <span word="received">received</span> <span word="remdesivir">remdesivir</span> <span word="had">had</span> <span word="a">a</span> 31 <span word="percent">percent</span> <span word="faster">faster</span> <span word="time">time</span> <span word="to">to</span> <span word="recovery">recovery</span> <span word="than">than</span> <span word="those">those</span> <span word="who">who</span> <span word="received">received</span> <span word="placebo">placebo</span>, <span word="according">according</span> <span word="to">to</span> <span word="the">the</span> <span word="release">release</span>.</p><p><span word="Specifically">Specifically</span>, <span word="the">the</span> <span word="median">median</span> <span word="time">time</span> <span word="to">to</span> <span word="recovery">recovery</span> <span word="was">was</span> 11 <span word="days">days</span> <span word="for">for</span> <span word="patients">patients</span> <span word="treated">treated</span> <span word="with">with</span> <span word="remdesivir">remdesivir</span> <span word="compared">compared</span> <span word="with">with</span> 15 <span word="days">days</span> <span word="for">for</span> <span word="those">those</span> <span word="who">who</span> <span word="received">received</span> <span word="placebo">placebo</span>.</p><p><span word="The">The</span> <span word="results">results</span> <span word="also">also</span> <span word="suggested">suggested</span> <span word="a">a</span> <span word="survival">survival</span> <span word="benefit">benefit</span>, <span word="with">with</span> <span word="a">a</span> <span word="mortality">mortality</span> <span word="rate">rate</span> <span word="of">of</span> 8 <span word="percent">percent</span> <span word="for">for</span> <span word="the">the</span> <span word="group">group</span> <span word="receiving">receiving</span> <span word="remdesivir">remdesivir</span> <span word="versus">versus</span> 11.6 <span word="percent">percent</span> <span word="for">for</span> <span word="the">the</span> <span word="placebo">placebo</span> <span word="group">group</span>.</p><p><span word="An">An</span> <span word="independent">independent</span> <span word="data">data</span> <span word="and">and</span> <span word="safety">safety</span> <span word="monitoring">monitoring</span> <span word="board">board</span> <span word="overseeing">overseeing</span> <span word="the">the</span> <span word="trial">trial</span> <span word="met">met</span> <span word="on">on</span> <span word="April">April</span> 27 <span word="to">to</span> <span word="review">review</span> <span word="the">the</span> <span word="data">data</span> <span word="and">and</span> <span word="shared">shared</span> <span word="their">their</span> <span word="interim">interim</span> <span word="analysis">analysis</span> <span word="with">with</span> <span word="the">the</span> <span word="study">study</span> <span word="team">team</span>.</p><p><span word="Based">Based</span> <span word="upon">upon</span> <span word="their">their</span> <span word="review">review</span> <span word="of">of</span> <span word="the">the</span> <span word="data">data</span>, <span word="the">the</span> <span word="board">board</span> <span word="members">members</span> <span word="noted">noted</span> <span word="that">that</span> <span word="remdesivir">remdesivir</span> <span word="was">was</span> <span word="better">better</span> <span word="than">than</span> <span word="placebo">placebo</span> <span word="from">from</span> <span word="the">the</span> <span word="perspective">perspective</span> <span word="of">of</span> <span word="primary">primary</span> <span word="endpoint">endpoint</span>, <span word="or">or</span> <span word="patients">patients</span>' <span word="time">time</span> <span word="to">to</span> <span word="recovery">recovery</span>. <span word="It">It</span> <span word="is">is</span> <span word="a">a</span> <span word="metric">metric</span> <span word="often">often</span> <span word="used">used</span> <span word="in">in</span> <span word="influenza">influenza</span> <span word="trials">trials</span>.</p><p><span word="The">The</span> <span word="first">first</span> <span word="participant">participant</span> <span word="in">in</span> <span word="the">the</span> <span word="trial">trial</span> <span word="was">was</span> <span word="an">an</span> <span word="American">American</span> <span word="who">who</span> <span word="was">was</span> <span word="repatriated">repatriated</span> <span word="after">after</span> <span word="being">being</span> <span word="quarantined">quarantined</span> <span word="on">on</span> <span word="the">the</span> <span word="Diamond">Diamond</span> <span word="Princess">Princess</span> <span word="cruise">cruise</span> <span word="ship">ship</span> <span word="that">that</span> <span word="docked">docked</span> <span word="in">in</span> <span word="Yokohama">Yokohama</span>, <span word="Japan">Japan</span>.</p>
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