科学家找到决定怀孕成功的关键基因！
<p>一项研究显示，<span word="OCT">OCT</span>4基因在人类胚胎早期发育阶段是必需的，当它的表达受到抑制时，发育将受到影响。这一发现改变了人们对流产和不孕的根本原因的认识，也预示着试管婴儿的成功率可能将提高。</p><p><span word="Scientists">Scientists</span> <span word="have">have</span> <span word="edited">edited</span> <span word="human">human</span> <span word="embryos">embryos</span> <span word="for">for</span> <span word="the">the</span> <span word="first">first</span> <span word="time">time</span> <span word="in">in</span> <span word="the">the</span> <span word="UK">UK</span> <span word="to">to</span> <span word="discover">discover</span> <span word="a">a</span> “<span word="master">master</span> <span word="gene">gene</span>” <span word="that">that</span> <span word="underpins">underpins</span> <span word="successful">successful</span> <span word="pregnancies">pregnancies</span>. <span word="The">The</span> “<span word="game">game</span>-<span word="changing">changing</span>” <span word="research">research</span> <span word="promises">promises</span> <span word="improved">improved</span> <span word="IVF">IVF</span> <span word="outcomes">outcomes</span> <span word="and">and</span> <span word="a">a</span> <span word="breakthrough">breakthrough</span> <span word="in">in</span> <span word="understanding">understanding</span> <span word="why">why</span> <span word="so">so</span> <span word="many">many</span> <span word="pregnancies">pregnancies</span> <span word="fail">fail</span>.</p><p>科学家首次在英国对人类胚胎进行编辑，他们发现了一种为妊娠成功奠定基础的“主导基因”。这项“划时代”的研究有望提高体外受精成功率，并有助于了解很多人妊娠失败的原因。</p><p><span word="The">The</span> <span word="Government">Government</span>-<span word="funded">funded</span> <span word="investigation">investigation</span>, <span word="undertaken">undertaken</span> <span word="by">by</span> <span word="the">the</span> <span word="Francis">Francis</span> <span word="Crick">Crick</span> <span word="Institute">Institute</span>, <span word="is">is</span> <span word="the">the</span> <span word="first">first</span> <span word="to">to</span> <span word="prove">prove</span> <span word="that">that</span> <span word="gene">gene</span> <span word="editing">editing</span> <span word="can">can</span> <span word="be">be</span> <span word="used">used</span> <span word="to">to</span> <span word="study">study</span> <span word="the">the</span> <span word="genetic">genetic</span> <span word="behavior">behavior</span> <span word="of">of</span> <span word="human">human</span> <span word="embryos">embryos</span> <span word="in">in</span> <span word="their">their</span> <span word="first">first</span> <span word="few">few</span> <span word="days">days</span> <span word="of">of</span> <span word="life">life</span>.</p><p>弗兰西斯克里克研究所在政府的资助下进行了这项研究，首次证明可以利用基因编辑研究人类胚胎发育最初阶段的遗传行为。</p><p><span word="By">By</span> <span word="removing">removing</span> <span word="a">a</span> <span word="gene">gene</span> <span word="which">which</span> <span word="produces">produces</span> <span word="a">a</span> <span word="protein">protein</span> <span word="called">called</span> <span word="OCT">OCT</span>4, <span word="the">the</span> <span word="team">team</span> <span word="discovered">discovered</span> <span word="it">it</span> <span word="was">was</span> <span word="crucial">crucial</span> <span word="to">to</span> <span word="a">a</span> <span word="viable">viable</span> <span word="pregnancy">pregnancy</span>.</p><p>通过移除一种名为<span word="OCT">OCT</span>4的蛋白质生成基因，研究团队发现，该基因正是成功妊娠的关键。</p><p><span word="As">As</span> <span word="well">well</span> <span word="as">as</span> <span word="its">its</span> <span word="potential">potential</span> <span word="for">for</span> <span word="more">more</span> <span word="successful">successful</span> <span word="IVF">IVF</span>, <span word="the">the</span> <span word="discovery">discovery</span> <span word="heralds">heralds</span> <span word="a">a</span> <span word="transformation">transformation</span> <span word="in">in</span> <span word="understanding">understanding</span> <span word="the">the</span> <span word="fundamental">fundamental</span> <span word="causes">causes</span> <span word="of">of</span> <span word="infertility">infertility</span> <span word="and">and</span> <span word="miscarriage">miscarriage</span>.</p>
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