患上痛风也许让你不得老年痴呆症
<p><span word="Gout">Gout</span>, <span word="a">a</span> <span word="form">form</span> <span word="of">of</span> <span word="arthritis">arthritis</span>, <span word="is">is</span> <span word="extremely">extremely</span> <span word="painful">painful</span> <span word="and">and</span> <span word="associated">associated</span> <span word="with">with</span> <span word="an">an</span> <span word="increased">increased</span> <span word="risk">risk</span> <span word="for">for</span> <span word="cardiovascular">cardiovascular</span> <span word="problems">problems</span>. <span word="But">But</span> <span word="there">there</span> <span word="is">is</span> <span word="a">a</span> <span word="bright">bright</span> <span word="side">side</span>: <span word="It">It</span> <span word="may">may</span> <span word="be">be</span> <span word="linked">linked</span> <span word="to">to</span> <span word="a">a</span> <span word="reduced">reduced</span> <span word="risk">risk</span> <span word="for">for</span> <span word="Alzheimer">Alzheimer</span>’<span word="s">s</span> <span word="disease">disease</span>.</p><p>痛风是关节炎的一种，它很折磨人，而且与心血管疾病风险增加有关。但它也有好的一面：它可能与老年痴呆症风险降低有关。</p><p><span word="Researchers">Researchers</span> <span word="compared">compared</span> 59,204 <span word="British">British</span> <span word="men">men</span> <span word="and">and</span> <span word="women">women</span> <span word="with">with</span> <span word="gout">gout</span> <span word="to">to</span> 238,805 <span word="without">without</span> <span word="the">the</span> <span word="ailment">ailment</span>, <span word="with">with</span> <span word="an">an</span> <span word="average">average</span> <span word="age">age</span> <span word="of">of</span> 65. <span word="Patients">Patients</span> <span word="were">were</span> <span word="matched">matched</span> <span word="for">for</span> <span word="sex">sex</span>, <span word="B">B</span>.<span word="M">M</span>.<span word="I">I</span>., <span word="smoking">smoking</span>, <span word="alcohol">alcohol</span> <span word="consumption">consumption</span> <span word="and">and</span> <span word="other">other</span> <span word="characteristics">characteristics</span>. <span word="The">The</span> <span word="study">study</span>, <span word="in">in</span> <span word="The">The</span> <span word="Annals">Annals</span> <span word="of">of</span> <span word="the">the</span> <span word="Rheumatic">Rheumatic</span> <span word="Diseases">Diseases</span>, <span word="followed">followed</span> <span word="the">the</span> <span word="patients">patients</span> <span word="for">for</span> <span word="five">five</span> <span word="years">years</span>.</p><p>研究人员花了五年时间对英国的59204名痛风患者和238805名非痛风患者进行比较。他们的平均年龄为65岁，在性行为、体重指数、吸烟、喝酒等方面都比较接近。这项研究发表在《风湿病疾病纪事》(<span word="The">The</span> <span word="Annals">Annals</span> <span word="of">of</span> <span word="the">the</span> <span word="Rheumatic">Rheumatic</span> <span word="Diseases">Diseases</span>)上。</p><p><span word="They">They</span> <span word="found">found</span> 309 <span word="cases">cases</span> <span word="of">of</span> <span word="Alzheimer">Alzheimer</span>’<span word="s">s</span> <span word="among">among</span> <span word="those">those</span> <span word="with">with</span> <span word="gout">gout</span> <span word="and">and</span> 1,942 <span word="among">among</span> <span word="those">those</span> <span word="without">without</span>. <span word="Those">Those</span> <span word="with">with</span> <span word="gout">gout</span>, <span word="whether">whether</span> <span word="they">they</span> <span word="were">were</span> <span word="being">being</span> <span word="treated">treated</span> <span word="for">for</span> <span word="the">the</span> <span word="condition">condition</span> <span word="or">or</span> <span word="not">not</span>, <span word="had">had</span> <span word="a">a</span> 24 <span word="percent">percent</span> <span word="lower">lower</span> <span word="risk">risk</span> <span word="of">of</span> <span word="Alzheimer">Alzheimer</span>’<span word="s">s</span> <span word="disease">disease</span>.</p><p>他们发现，痛风患者中有309个老年痴呆症病例，非痛风患者中有1942个病例。不管是否正在接受痛风治疗，痛风患者得老年痴呆症的比例比另一组低24%。</p><p><span word="The">The</span> <span word="reason">reason</span> <span word="for">for</span> <span word="the">the</span> <span word="connection">connection</span> <span word="is">is</span> <span word="unclear">unclear</span>. <span word="But">But</span> <span word="gout">gout</span> <span word="is">is</span> <span word="caused">caused</span> <span word="by">by</span> <span word="excessive">excessive</span> <span word="levels">levels</span> <span word="of">of</span> <span word="uric">uric</span> <span word="acid">acid</span> <span word="in">in</span> <span word="the">the</span> <span word="blood">blood</span>, <span word="and">and</span> <span word="previous">previous</span> <span word="studies">studies</span> <span word="have">have</span> <span word="suggested">suggested</span> <span word="that">that</span> <span word="uric">uric</span> <span word="acid">acid</span> <span word="protects">protects</span> <span word="against">against</span> <span word="oxidative">oxidative</span> <span word="stress">stress</span>. <span word="This">This</span> <span word="may">may</span> <span word="play">play</span> <span word="a">a</span> <span word="role">role</span> <span word="in">in</span> <span word="limiting">limiting</span> <span word="neuron">neuron</span> <span word="degeneration">degeneration</span>.</p>
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