中国科学家基因编辑治疗艾滋病 向"治愈"又迈出一步
<p><span word="The">The</span> 27-<span word="year">year</span>-<span word="old">old</span> <span word="patient">patient</span>'<span word="s">s</span> <span word="prospects">prospects</span> <span word="were">were</span> <span word="bleak">bleak</span>. <span word="In">In</span> <span word="May">May</span> 2016, <span word="he">he</span> <span word="found">found</span> <span word="out">out</span> <span word="he">he</span> <span word="had">had</span> <span word="AIDS">AIDS</span>. <span word="Two">Two</span> <span word="weeks">weeks</span> <span word="later">later</span>, <span word="he">he</span> <span word="was">was</span> <span word="told">told</span> <span word="he">he</span> <span word="had">had</span> <span word="acute">acute</span> <span word="lymphoblastic">lymphoblastic</span> <span word="leukemia">leukemia</span>.</p><p>这位27岁的病人前景黯淡。2016年5月，他发现自己患有艾滋病。两周后，他被告知患有急性淋巴细胞白血病。</p><p><span word="But">But</span> <span word="doctors">doctors</span> <span word="offered">offered</span> <span word="the">the</span> <span word="Chinese">Chinese</span> <span word="citizen">citizen</span> <span word="a">a</span> <span word="ray">ray</span> <span word="of">of</span> <span word="hope">hope</span>: <span word="a">a</span> <span word="bone">bone</span> <span word="marrow">marrow</span> <span word="transplant">transplant</span> <span word="to">to</span> <span word="treat">treat</span> <span word="his">his</span> <span word="cancer">cancer</span> <span word="and">and</span> <span word="an">an</span> <span word="extra">extra</span> <span word="experimental">experimental</span> <span word="treatment">treatment</span> <span word="to">to</span> <span word="try">try</span> <span word="to">to</span> <span word="rid">rid</span> <span word="his">his</span> <span word="system">system</span> <span word="of">of</span> <span word="HIV">HIV</span>, <span word="according">according</span> <span word="to">to</span> <span word="a">a</span> <span word="new">new</span> <span word="paper">paper</span> <span word="published">published</span> <span word="in">in</span> <span word="The">The</span> <span word="New">New</span> <span word="England">England</span> <span word="Journal">Journal</span> <span word="of">of</span> <span word="Medicine">Medicine</span>.</p><p>但根据《新英格兰医学杂志》最新发表的一篇论文，医生们给这位中国公民带来了一线希望：通过骨髓移植来治疗他的癌症，并进行另外的实验性治疗，试图清除他体内的艾滋病病毒。</p><p><span word="This">This</span> <span word="involved">involved</span> <span word="using">using</span> <span word="the">the</span> <span word="gene">gene</span> <span word="editing">editing</span> <span word="tool">tool</span> <span word="CRISPR">CRISPR</span>-<span word="Cas">Cas</span>9 <span word="to">to</span> <span word="delete">delete</span> <span word="a">a</span> <span word="gene">gene</span> <span word="known">known</span> <span word="as">as</span> <span word="CCR">CCR</span>5 <span word="from">from</span> <span word="bone">bone</span> <span word="marrow">marrow</span> <span word="stem">stem</span> <span word="cells">cells</span> <span word="taken">taken</span> <span word="from">from</span> <span word="a">a</span> <span word="donor">donor</span>, <span word="before">before</span> <span word="transplanting">transplanting</span> <span word="them">them</span> <span word="into">into</span> <span word="the">the</span> <span word="patient">patient</span>, <span word="Peking">Peking</span> <span word="University">University</span> <span word="scientists">scientists</span> <span word="said">said</span> <span word="in">in</span> <span word="the">the</span> <span word="study">study</span>.</p><p>参与研究的北京大学科学家说，治疗手段包括使用基因编辑工具<span word="CRISPR">CRISPR</span>-<span word="Cas">Cas</span>9从捐赠者的骨髓干细胞中删除一种名为<span word="CCR">CCR</span>5的基因，然后将干细胞移植到患者体内。</p>
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