我国科学家发现了可抑制HIV扩散的蛋白质
<p><span word="Chinese">Chinese</span> <span word="scientists">scientists</span> <span word="have">have</span> <span word="identified">identified</span> <span word="a">a</span> <span word="new">new</span> <span word="protein">protein</span> <span word="that">that</span> <span word="restricts">restricts</span> <span word="HIV">HIV</span> <span word="infection">infection</span>, <span word="which">which</span> <span word="could">could</span> <span word="pave">pave</span> <span word="way">way</span> <span word="for">for</span> <span word="development">development</span> <span word="of">of</span> <span word="new">new</span> <span word="antivirus">antivirus</span> <span word="drugs">drugs</span>.</p><p>我国科学家已经发现了一种新的可抑制<span word="HIV">HIV</span>感染的蛋白质，此发现将为新的抗病毒药物的研发奠定基础。</p><p><span word="The">The</span> <span word="protein">protein</span>, <span word="P">P</span>-<span word="selectin">selectin</span> <span word="glycoprotein">glycoprotein</span> <span word="ligand">ligand</span> 1 (<span word="PSGL">PSGL</span>-1), <span word="can">can</span> <span word="inhibit">inhibit</span> <span word="HIV">HIV</span> <span word="reverse">reverse</span> <span word="transcription">transcription</span> <span word="and">and</span> <span word="effectively">effectively</span> <span word="block">block</span> <span word="its">its</span> <span word="viral">viral</span> <span word="infectivity">infectivity</span>, <span word="according">according</span> <span word="to">to</span> <span word="the">the</span> <span word="research">research</span>, <span word="published">published</span> <span word="on">on</span> <span word="science">science</span> <span word="journal">journal</span> <span word="Nature">Nature</span> <span word="earlier">earlier</span> <span word="this">this</span> <span word="month">month</span>.</p><p>本月早些时候发表在科学杂志《自然》(<span word="Nature">Nature</span>)上的一项研究表明，这种名为<span word="p">p</span>-选择素糖蛋白配体1 (<span word="PSGL">PSGL</span>-1)的蛋白质能够抑制<span word="HIV">HIV</span>的逆转录，并有效地阻止其病毒感染。</p><p><span word="The">The</span> <span word="study">study</span>, <span word="conducted">conducted</span> <span word="by">by</span> <span word="researchers">researchers</span> <span word="from">from</span> <span word="universities">universities</span> <span word="including">including</span> <span word="Tsinghua">Tsinghua</span> <span word="University">University</span> <span word="in">in</span> <span word="Beijing">Beijing</span>, <span word="and">and</span> <span word="Fudan">Fudan</span> <span word="University">University</span> <span word="in">in</span> <span word="Shanghai">Shanghai</span>, <span word="also">also</span> <span word="showed">showed</span> <span word="PSGL">PSGL</span>-1 <span word="can">can</span> <span word="be">be</span> <span word="down">down</span> <span word="regulated">regulated</span> <span word="by">by</span> <span word="HIV">HIV</span>-1 <span word="Vpu">Vpu</span>, <span word="an">an</span> <span word="accessory">accessory</span> <span word="protein">protein</span> <span word="of">of</span> <span word="HIV">HIV</span>, <span word="so">so</span> <span word="it">it</span> <span word="fails">fails</span> <span word="to">to</span> <span word="resist">resist</span> <span word="HIV">HIV</span> <span word="infection">infection</span>.</p><p>北京清华大学和上海复旦大学研究人员组成的研究小组所发表的研究也表明，<span word="HIV">HIV</span>的附属蛋白<span word="HIV">HIV</span>-1 <span word="Vpu">Vpu</span>对<span word="PSGL">PSGL</span>-1有向下调节作用，所以它未能阻止<span word="HIV">HIV</span>的传染。</p><p><span word="Further">Further</span> <span word="research">research</span> <span word="is">is</span> <span word="underway">underway</span> <span word="to">to</span> <span word="develop">develop</span> <span word="a">a</span> <span word="drug">drug</span> <span word="that">that</span> <span word="can">can</span> <span word="inhibit">inhibit</span> <span word="the">the</span> <span word="HIV">HIV</span> <span word="protein">protein</span> <span word="so">so</span> <span word="PSGL">PSGL</span>-1 <span word="can">can</span> <span word="work">work</span> <span word="to">to</span> <span word="resist">resist</span> <span word="HIV">HIV</span>.</p><p>能够抑制<span word="HIV">HIV</span>蛋白的药物研究正在进一步开展，以便<span word="PSGL">PSGL</span>-1能够运作起来对抗<span word="HIV">HIV</span>。</p>
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