超重或导致患胰腺癌的风险增加
<p><span word="Pancreatic">Pancreatic</span> <span word="cancer">cancer</span> <span word="rates">rates</span> <span word="have">have</span> <span word="increased">increased</span> <span word="by">by</span> <span word="nearly">nearly</span> <span word="a">a</span> <span word="fifth">fifth</span> <span word="since">since</span> 1999.</p><p>自1999年以来，胰腺癌的发病率已增加近五分之一。</p><p><span word="Smoking">Smoking</span> <span word="is">is</span> <span word="a">a</span> <span word="known">known</span> <span word="cause">cause</span> <span word="of">of</span> <span word="this">this</span> <span word="often">often</span>-<span word="fatal">fatal</span> <span word="disease">disease</span> <span word="yet">yet</span> <span word="the">the</span> <span word="number">number</span> <span word="of">of</span> <span word="smokers">smokers</span> <span word="has">has</span> <span word="reached">reached</span> <span word="a">a</span> <span word="record">record</span> <span word="low">low</span> <span word="while">while</span> <span word="pancreatic">pancreatic</span> <span word="cancer">cancer</span> <span word="rates">rates</span> <span word="continue">continue</span> <span word="to">to</span> <span word="climb">climb</span>. <span word="Could">Could</span> <span word="the">the</span> <span word="obesity">obesity</span> <span word="epidemic">epidemic</span> <span word="now">now</span> <span word="be">be</span> <span word="fuelling">fuelling</span> <span word="the">the</span> <span word="increase">increase</span> <span word="in">in</span> <span word="pancreatic">pancreatic</span> <span word="cancer">cancer</span> <span word="rates">rates</span>? <span word="How">How</span> <span word="does">does</span> <span word="it">it</span> <span word="do">do</span> <span word="this">this</span>?</p><p>众所周知，吸烟是这种常见致命疾病的诱因之一，但现而今，吸烟人数已达历史最低，而胰腺癌的发病率仍在继续攀升。肥胖症是否也在助推胰腺癌发病率的上升？它又是如何做到的？</p><p><span word="Obesity">Obesity</span> <span word="causes">causes</span> <span word="inflammation">inflammation</span>, <span word="which">which</span> <span word="encourages">encourages</span> <span word="cell">cell</span> <span word="growth">growth</span> <span word="and">and</span> <span word="can">can</span> <span word="promote">promote</span> <span word="cancer">cancer</span> <span word="cell">cell</span> <span word="mutations">mutations</span>. <span word="Unsurprisingly">Unsurprisingly</span>, <span word="people">people</span> <span word="who">who</span> <span word="have">have</span> <span word="a">a</span> <span word="BMI">BMI</span> <span word="over">over</span> 30 <span word="before">before</span> <span word="the">the</span> <span word="age">age</span> <span word="of">of</span> 50 <span word="are">are</span> <span word="at">at</span> <span word="a">a</span> 25% <span word="greater">greater</span> <span word="risk">risk</span> <span word="of">of</span> <span word="dying">dying</span> <span word="of">of</span> <span word="pancreatic">pancreatic</span> <span word="cancer">cancer</span>.</p><p>肥胖会引发炎症，从而促进细胞生长、加快癌细胞突变。果不其然，50岁以前身体质量指数超过30的人因胰腺癌而亡的风险会增加25%。</p><p>"<span word="We">We</span>'<span word="ve">ve</span> <span word="been">been</span> <span word="puzzled">puzzled</span> <span word="by">by</span> <span word="that">that</span> <span word="increase">increase</span> <span word="because">because</span> <span word="smoking">smoking</span> - <span word="a">a</span> <span word="major">major</span> <span word="risk">risk</span> <span word="factor">factor</span> <span word="for">for</span> <span word="pancreatic">pancreatic</span> <span word="cancer">cancer</span> - <span word="is">is</span> <span word="declining">declining</span>," <span word="Dr">Dr</span> <span word="Eric">Eric</span> <span word="Jacobs">Jacobs</span>, <span word="scientific">scientific</span> <span word="director">director</span> <span word="at">at</span> <span word="the">the</span> <span word="American">American</span> <span word="Cancer">Cancer</span> <span word="Society">Society</span>, <span word="and">and</span> <span word="co">co</span>-<span word="author">author</span> <span word="of">of</span> <span word="the">the</span> <span word="new">new</span> <span word="study">study</span> <span word="has">has</span> <span word="said">said</span>.</p><p>"我们一直对胰腺癌发病率上升一事感到困惑，因为吸烟--胰腺癌的主要危险因素--正在下降，"美国癌症协会的科学主任兼本项新研究的合著者埃里克·雅各布（<span word="Eric">Eric</span> <span word="Jacobs">Jacobs</span>）博士说道。</p>
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