遗传研究揭秘人类的潜在寿命
<p><span word="A">A</span> <span word="study">study</span> <span word="presented">presented</span> <span word="at">at</span> <span word="the">the</span> <span word="just">just</span>-<span word="finished">finished</span> <span word="American">American</span> <span word="Society">Society</span> <span word="of">of</span> <span word="Human">Human</span> <span word="Genetics">Genetics</span> 2018 <span word="Annual">Annual</span> <span word="Meeting">Meeting</span> <span word="in">in</span> <span word="San">San</span> <span word="Diego">Diego</span> <span word="reported">reported</span> <span word="a">a</span> <span word="way">way</span> <span word="to">to</span> <span word="estimate">estimate</span> <span word="whether">whether</span> <span word="an">an</span> <span word="individual">individual</span> <span word="can">can</span> <span word="expect">expect</span> <span word="to">to</span> <span word="live">live</span> <span word="longer">longer</span> <span word="or">or</span> <span word="shorter">shorter</span> <span word="than">than</span> <span word="average">average</span>.</p><p>前不久，在圣地亚哥举行的2018年美国人类遗传学会年会上，一项研究报道了一种方法，可评估个体活得比平均寿命更长或更短。</p><p><span word="An">An</span> <span word="international">international</span> <span word="research">research</span> <span word="group">group</span> <span word="studied">studied</span> <span word="the">the</span> <span word="effect">effect</span> <span word="of">of</span> <span word="genetic">genetic</span> <span word="variations">variations</span> <span word="on">on</span> <span word="lifespan">lifespan</span> <span word="across">across</span> <span word="the">the</span> <span word="human">human</span> <span word="genome">genome</span>, <span word="which">which</span> <span word="could">could</span> <span word="improve">improve</span> <span word="our">our</span> <span word="understanding">understanding</span> <span word="of">of</span> <span word="the">the</span> <span word="diseases">diseases</span> <span word="and">and</span> <span word="cellular">cellular</span> <span word="pathways">pathways</span> <span word="involved">involved</span> <span word="in">in</span> <span word="aging">aging</span>.</p><p>国际研究小组研究了遗传变异对整个人类基因组寿命的影响，或能提高我们对老年疾病以及与年老相关的细胞通路的认知。</p><p><span word="In">In</span> <span word="the">the</span> <span word="largest">largest</span> <span word="ever">ever</span> <span word="genome">genome</span>-<span word="wide">wide</span> <span word="association">association</span> <span word="study">study</span> <span word="of">of</span> <span word="lifespan">lifespan</span>, <span word="the">the</span> <span word="researchers">researchers</span> <span word="paired">paired</span> <span word="genetic">genetic</span> <span word="data">data</span> <span word="from">from</span> <span word="more">more</span> <span word="than">than</span> 500,000 <span word="participants">participants</span> <span word="in">in</span> <span word="the">the</span> <span word="United">United</span> <span word="Kingdom">Kingdom</span> <span word="Biobank">Biobank</span> <span word="and">and</span> <span word="other">other</span> <span word="cohorts">cohorts</span> <span word="with">with</span> <span word="data">data</span> <span word="on">on</span> <span word="the">the</span> <span word="lifespan">lifespan</span> <span word="of">of</span> <span word="each">each</span> <span word="participant">participant</span>'<span word="s">s</span> <span word="parents">parents</span>.</p><p>在这项有史以来规模最大的全基因组与寿命的关联研究中，研究员将来自英国生物银行和其它来源的50多万名参与者的遗传数据与每位参与者父母的寿命数据进行配对。</p>
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